Osteoponin Promoter Controlled by DNA Methylation: Aberrant Methylation in Cloned Porcine Genome

<table>The bisulfite sequencing of<i> OPN</i> −2610~<svg height="0.125" id="M4" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 0.125 0.125" width="0.125" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
</svg>  −2400 nt upstream the promoter in cloned pigs’ tissues. The closed circles represent the methylation CpG sites. The hollow circles represent the unmethylated CpG sites. The bottom number indicated the methylation percentage of each sample. The range of square showed that the region may be the methylation controlled region of<i> OPN</i> promoter.</table>

BioMed Research International

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Figure 4

Figure 4: Osteoponin Promoter Controlled by DNA Methylation: Aberrant Methylation in Cloned Porcine Genome 