Research Article

Recovery of Peripheral Nerve with Massive Loss Defect by Tissue Engineered Guiding Regenerative Gel

Table 1


Number of ratsTreatment of the segmental 15 mm loss*Experimental length in time

8Control operated and further implanted with autogenous peripheral nerve graft90 days
8Bridged with standard tube only90 days
8Bridged with standard tube and filled with gel vehicle including HA only90 days
8Bridged with standard tube filled with GRG90 days

In rats model, regeneration within empty tube is possible when gap is up to 7 mm long.