BioMed Research International / 2014 / Article / Tab 2 / Review Article
Laparoscopic Resection for Rectal Cancer: What Is the Evidence? Table 2 Long-term outcomes-oncological.
Trial Type Surgical method in comparison Numbers Median follow-up period (months) Local recurrence Neoadjuvant therapy administered Disease-free survival (months) Median overall survival (months) CLASICC [3 ] Multicentre RCT—UK Open versus laparoscopic assisted 254 (O) versus 127 (L) 62.9 in both arms NA Not controlled 67.1 versus 70.8 65.8 versus 82.7 Lujan et al. [18 ] Single centre RCT—Spain Open versus laparoscopic assisted 103 versus 101 34.1, 32.8 5.3 versus 4.8 77 versus 73, no statistical significance 81.0 versus 84.8 75.3 versus 72.1 Ng et al. [20 ] Single centre RCT—UK Open versus laparoscopic assisted 142 versus 136 136.6, 124.5 9.3 versus 5.5 Neoadjuvant not included in trial * +
Trial calculated probability of being disease-free at 15 years, 71.4% versus 79%.
+ Trial calculated probability of overall survival at 15 years, 51.4% versus 47.4%.