Developing eThread Pipeline Using SAGA-Pilot Abstraction for Large-Scale Structural Bioinformatics

Algorithm 1

Serial algorithm for eThread.

Data: 𝑁 protein gene sequences

Result: Gene annotation and tertiary structure

for 𝑖=1 to 𝑁 do

   read 𝑖th sequence

   foreach 10 threading tools do

       if pre-processing then

     do pre-processing

       end

       do domain processing

       do chain processing

       do post-processing

       write output

   end

   /∗    now meta-analysis step using all

        outputs from 10 threading tools

        ∗/

   read all outputs

   do meta-analysis

end