Developing eThread Pipeline Using SAGA-Pilot Abstraction for Large-Scale Structural Bioinformatics

Figure 1

Schematics of the pilot-based eThread pipeline on EC2. The eThread pipeline can accept a massive number of sequences, identified from genome-wide sequencing methods such as RNA-Seq, for example, as input, and carry out metathreading-based structural bioinformatics analysis including structure modeling. SAGA-Pilot enables its execution on Amazon EC2 cloud environment to be efficient by facilitating data and task-level parallelization.