Deregulation of Serum MicroRNA Expression Is Associated with Cigarette Smoking and Lung Cancer
Table 2
Candidate miRNAs selected from the miRNAs with differential expression profiles on a microarray analysis.
Name of miRNA
(S versus C*) Fold change
Foreground-backgroun
(T versus C) Fold-change
Foreground-background
C
S
C
T
Upregulated
hsa-miR-7-5p
4.26
1045
4638
3.53
1045
4214
hsa-miR-502-3p
7.05
206
1511
6.33
206
1488
hsa-miR-200c-5p
5.34
178
989
3.72
178
754
hsa-miR-1301
6.52
122
832
3.42
122
478
Downregulated
hsa-miR-154-5p
3.4
419
128
3.96
419
120
hsa-let-7i-3p
23.05
410
18.5
18.71
410
25
hsa-miR-129-2-3p
4.95
28
97
22.59
459
25
hsa-miR-196a-3p
6.81
626
95
8.25
626
86
C, S, and T represent nonsmoker controls, smokers, and lung-cancer patients, respectively. Foreground-background represents the signal of the probe after background correction.
