Clinical Study

A New Sampling Method for Spleen Stiffness Measurement Based on Quantitative Acoustic Radiation Force Impulse Elastography for Noninvasive Assessment of Esophageal Varices in Newly Diagnosed HCV-Related Cirrhosis

Table 2

Characteristics of cirrhotic patients with esophageal varices (EV) compared to cirrhotic patients without EV by Kruskal-Wallis test.

Cirrhotics with esophageal varices ( )Cirrhotics without esophageal varices ( )

Age (years)**76 (63–81)68 (62–75)
Sex, male/female*13 (46.4)/15 (53.6)12 (46.1)/14 (53.9)
HCV RNA * 105 (IU/mL)
HCV genotype 1/2/3/4*18 (64.3)/2 (7.1)/8 (28.6)/0 (0)20 (77)/2 (7.7)/4 (15.3)/0 ( )
Child-Pugh class A/B*8 (28.5)/20 (71.5)7 (27)/19 (73)
Total bilirubin (mg/dL)**1.9 (1–3.1)***1.1 (0.7–2.8)***
AST (IU/L)**55 (27–111)58 (21–105)
ALT (IU/L)**63 (39–136)69 (30–129)
Albumin (g/dL)**3.4 (2.1–3.6)3.9 (2.7–4.1)
Gamma globulins (g/dL)**3.0 (2.4–3.3)2.8 (2.1–3.1)
Platelet count * 103/ L**96 (34–206)***124 (65–212)***
International normalized ratio (INR)**1.11 (1–1.59)1.31 (1.23–1.97)
Echographic spleen diameter (cm)**14.1 (11.6–17.8)***11.8 (9.1–12.7)***

*Data presented as (%) **Data presented as median (IQR)  Data presented as mean ± standard deviation .
AST: aspartate aminotransferase; ALT: alanine aminotransferase; IQR: interquartile range.