The Structural Modeling of the Interaction between Levofloxacin and the Mycobacterium tuberculosis Gyrase Catalytic Site Sheds Light on the Mechanisms of Fluoroquinolones Resistant Tuberculosis in Colombian Clinical Isolates

Table 4

Interaction energy and hydrogen bond length between GyrA and LVX.

Complex	Interaction; energy	Hydrogen bonds (Arg98-LVX)	Hydrogen bonds (Asp94-LVX)
H37Rv-LVX	−970.83 kcal/mol	4.778 Å	2.599 Å
TBR-49-LVX	−955.83 kcal/mol	5.143 Å	2.673 Å
TBR-67-LVX	−866.48 kcal/mol	4.500 Å	—