Research Article

Alcohol Induced Mitochondrial Oxidative Stress and Alveolar Macrophage Dysfunction

Figure 4

Chronic EtOH exposure promoted mitochondrial depolarization and dysfunction in MH-S cells. MH-S cells were exposed to EtOH for 1d, 3d, and 5d (0.2%, ). Following ethanol exposure, MH-S cells were stained with TMRE for FACS analysis (a). In addition to ethanol, some MH-S cells were treated with mitoT for 5d before the ATP (b) or NAD+/NADH (c) levels were determined ( ). All values are expressed as mean ± SD and normalized to untreated conditions. for EtOH versus none.
371593.fig.004a
(a)
371593.fig.004b
(b)
371593.fig.004c
(c)