Research Article

Lymphangiogenesis and Its Correlation with the VEGF Expression and the Sentinel Lymph Node in Cutaneous Melanomas

Table 1

Clinical and pathological data of the study subjects.

SLN positive (20 cases)SLN negative (20 cases)

Median age58.8 (33–79)62.1 (30–82)
Sex
 Male13 (65%)12 (60%)
 Female7 (35%)8 (40%)
Site
 Upper extremity5 (25%)4 (20%)
 Lower extremity3 (15%)2 (10%)
 Head and neck1 (5%)2 (10%)
 Acral regions2 (10%)2 (10%)
 Trunk9 (45%)10 (50%)
Thickness range 0.57–14.0 mm0.2–12.0 mm
Clark’s level
 II1 (5%)2 (10%)
 III9 (45%)12 (60%)
 IV6 (30%)4 (20%)
 V4 (20%) 2 (10%)
Ulceration
 Absent6 (30%)16 (80%)
 Present 14 (70%)4 (20%)
Histotype
 SSM0 2 (10%)
 NM18 (90%)16 (80%)
 ALM2 (10%)2 (0%)
Lymphatic invasion
 Absent16 (80%)20 (100%)
 Present4 (20%)0