Effects of Shiga Toxin Type 2 on Maternal and Fetal Status in Rats in the Early Stage of Pregnancy
Figure 6
Stx2 localization in maternal kidney and histological evaluation. Stx2 was detected in glomerular and tubular cells of 0.5 ng Stx2/g bwt treated rats at 6 h after injection by immunohistochemistry (b). This assay was repeated at least twice. No staining was detected in control renal tissues (a). Glomerular epithelial adherences (black arrowhead) and tubular necrosis (black arrows) were observed in Stx2-treated rats at 6 days after injection (d) compared with the controls (c). (a, b): ×400; (c, d): ×200.
