Research Article

In Vitro Ultrastructural Changes of MCF-7 for Metastasise Bone Cancer and Induction of Apoptosis via Mitochondrial Cytochrome C Released by CaCO3/Dox Nanocrystals

Figure 14

TUNEL DNA fragmentation assay on MCF-7 cells after treatment with Dox loaded CaCO3 nanocrystal. (a) is untreated cells showing complete absent of green fluorescence colour while (b), (c), and (d) are treated cells for incubation period of 24, 48, and 72 h, respectively. The cells showed depicting of TUNEL positive stain progressively according to the duration period.
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