Nerve Injury-Induced c-Jun Activation in Schwann Cells Is JNK Independent

Figure 5

c-Jun in Schwann cells is activated by phosphorylation following in vitro axotomy. (a) pc-Jun immunopositive areas in the rat sciatic nerve after 6 h of culturing (edge of nerve to the right). Scale bar = 500 μm. (b) pc-Jun immunoreactivity in rat sciatic nerve sections after culturing for 10 min to 48 h in vitro. The immunopositive nuclei are expressed as a percentage of the total number of nuclei in the nerve sections. Mean values ± SEM, 𝑛=6. ^∗𝑃<0.05, and ^∗∗∗𝑃<0.001.

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