Formulation and Evaluation of Fixed-Dose Combination of Bilayer Gastroretentive Matrix Tablet Containing Atorvastatin as Fast-Release and Atenolol as Sustained-Release

<table>Dissolution profile of atorvastatin from physical mixtures and solvent evaporation products containing atorvastatin and <i>β</i>-CD in 1 : 1, 1 : 2, and 1 : 3 (drug/CD) molar ratios in comparison to atorvastatin powder performed in 0.1 M HCl at <svg height="11.2875" id="M38" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 54.174999 11.2875" width="54.174999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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BioMed Research International

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Figure 5

Figure 5: Formulation and Evaluation of Fixed-Dose Combination of Bilayer Gastroretentive Matrix Tablet Containing Atorvastatin as Fast-Release and Atenolol as Sustained-Release 

Figure 5 | Formulation and Evaluation of Fixed-Dose Combination of Bilayer Gastroretentive Matrix Tablet Containing Atorvastatin as Fast-Release and Atenolol as Sustained-Release 