Research Article

Formulation and Evaluation of Fixed-Dose Combination of Bilayer Gastroretentive Matrix Tablet Containing Atorvastatin as Fast-Release and Atenolol as Sustained-Release

Table 1

Composition of atorvastatin fast-release tablet formulation.

Ingredient Amount (mg)

Atorvastatin- -CD solvent evaporation product in 1 : 3 (drug/CD) molar ratio40.00
Sodium starch glycolate 5.00
Magnesium stearate 1.08
Talc 5.40
Dicalcium phosphate q.s.
Total weight 120.00

q.s.: quantity sufficient.