Research Article
Rho GTPase-Activating Protein 35 rs1052667 Polymorphism and Osteosarcoma Risk and Prognosis
Table 5
The rs1052667 polymorphism of ARHGAP35 and clinic pathological features of osteosarcoma.
| Variable | rs1052667-CC | rs1052667-CT/TT | OS (95% CI) | | | | | |
| Age (yrs) | | | | | | | 26 | 80 | 60.2 | 81 | 71.1 | 1 | | 26 | 53 | 39.8 | 33 | 28.9 | 0.72 (0.39–1.35) | 0.31 | Gender | | | | | | | Female | 49 | 36.8 | 44 | 38.6 | 1 | | Male | 84 | 63.2 | 70 | 61.4 | 1.07 (0.61–1.89) | 0.82 | Race | | | | | | | Han | 82 | 61.7 | 77 | 67.5 | 1 | | Minority | 51 | 38.3 | 37 | 32.5 | 0.98 (0.54–1.77) | 0.95 | Tumor site | | | | | | | Femur | 72 | 54.1 | 68 | 59.6 | 1 | | Tibia | 30 | 22.6 | 21 | 18.4 | 0.66 (0.32–1.33) | 0.24 | Humeral bone | 22 | 16.5 | 16 | 14 | 0.90 (0.40–2.01) | 0.79 | Others | 9 | 6.8 | 9 | 7.9 | 0.91 (0.31–2.70) | 0.86 | Tumor size | | | | | | | 5 cm | 57 | 42.9 | 15 | 13.2 | 1 | | 5 cm | 76 | 57.1 | 99 | 86.8 | 4.85 (2.51–9.37) | | Tumor grade | | | | | | | Low | 68 | 51.1 | 23 | 20.2 | 1 | | High | 65 | 48.9 | 91 | 79.8 | 4.07 (2.28–7.37) | | Metastasis | | | | | | | No | 87 | 65.4 | 45 | 39.5 | 1 | | Yes | 46 | 34.6 | 69 | 60.2 | 2.78 (1.63–4.76) | |
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