Research Article
Study of the Association between ITPKC Genetic Polymorphisms and Calcium Nephrolithiasis
Table 2
Association analysis of ITPKC single-nucleotide polymorphisms (SNPs) and clinical medical records data of patients with kidney stones.
| SNP | Genotype | Stone numbers (%) | value | Stone frequency (%) | value | Multiple | Single | Recurrence | Nonrecurrence |
| rs11673492 | TT | 12 (9.7) | 10 (8.1) | 0.9050 | 11 (9.7) | 10 (8.7) | 0.4025 | CT | 58 (46.8) | 59 (47.6) | 46 (40.7) | 57 (49.6) | CC | 54 (43.5) | 55 (44.3) | 56 (49.6) | 48 (41.7) |
| rs28493229 | CG | 18 (14.8) | 10 (8.1) | 0.1032 | 16 (14.4) | 9 (7.9) | 0.1198 | GG | 104 (85.2) | 113 (91.9) | 95 (85.6) | 105 (92.1) |
| rs7257602 | GG | 32 (25.8) | 24 (19.2) | 0.3705 | 27 (23.9) | 23 (19.8) | 0.7665 | AG | 55 (44.4) | 65 (52.0) | 54 (47.8) | 58 (50.0) | AA | 37 (29.8) | 36 (28.8) | 32 (28.3) | 35 (30.2) |
| rs7251246 | GG | 38 (30.7) | 30 (24.0) | 0.2634 | 29 (25.7) | 33 (28.5) | 0.7521 | GA | 50 (40.3) | 63 (50.4) | 52 (46.0) | 55 (47.4) | AA | 36 (29.0) | 32 (25.6) | 32 (28.3) | 28 (24.1) |
| rs890934 | TT | 23 (18.5) | 29 (23.2) | 0.3919 | 23 (20.3) | 24 (20.7) | 0.9975 | GT | 58 (46.8) | 62 (49.6) | 55 (48.7) | 56 (48.3) | GG | 43 (34.7) | 34 (27.2) | 35 (31.0) | 36 (31.0) |
| rs10420685 | GG | 7 (5.6) | 5 (4.0) | 0.7842 | 6 (5.3) | 6 (5.2) | 0.8333 | AG | 43 (34.7) | 41 (33.1) | 37 (32.7) | 42 (36.5) | AA | 74 (59.7) | 78 (62.9) | 70 (62.0) | 67 (58.3) |
| rs2607420 | CC | 10 (8.1) | 9 (7.2) | 0.9618 | 10 (8.9) | 9 (7.8) | 0.9191 | CT | 51 (41.5) | 52 (41.6) | 43 (38.4) | 47 (40.5) | TT | 62 (50.4) | 64 (51.2) | 59 (52.7) | 60 (51.7) |
| rs2290692 | GG | 38 (30.7) | 28 (22.4) | 0.2161 | 28 (24.8) | 32 (27.6) | 0.8602 | CG | 50 (40.3) | 63 (50.4) | 53 (46.9) | 54 (46.5) | CC | 36 (29.0) | 34 (27.2) | 32 (28.3) | 30 (25.9) |
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