The Emerging Use of In Vivo Optical Imaging in the Study of Neurodegenerative Diseases

Figure 3

Putative response element and transcription factor binding sites within the mouse GFAP 5′-upstream region. The binding sites of transcription factors and some elements are shown above the line. Hormone response elements binding sites are shown below the line. For a detailed description please refer to Laping et al. [14]. ThRE: thyroid hormone response factor element; ERE: estrogen response element; GRE: glucocorticoid response element, NF1: nuclear factor 1; AP2: activator protein 2; TIE: TGF-β inhibitory element; CRE: cAMP response element; NFκB: nuclear factor κB. Elements and features are not depicted to scale.