Research Article

Imaging Mass Spectrometry by Matrix-Assisted Laser Desorption/Ionization and Stress-Strain Measurements in Iontophoresis Transepithelial Corneal Collagen Cross-Linking

Table 3

Stress value for 4%, 6%, 8%, and 10% strains in rabbit corneas.

GroupsStress at 4% (103 Pa)Stress at 6% (103 Pa)Stress at 8% (103 Pa)Stress at 10% (103 Pa)

Group 1
 Untreated55.7 ± 17.16
( = 1.1 × 106 Pa)
101 ± 37.72
( = 1.8 × 106 Pa)
171.3 ± 73.89
( = 3 × 106 Pa)
270.3 ± 119.1
( = 4.8 × 106 Pa)
 Treated51.3 ± 11.8
( = 1 × 106 Pa)
93.7 ± 29.5
( = 1.7 × 106 Pa)
157.7 ± 59.7
( = 2.7 × 106 Pa)
249.0 ± 100.5
( = 4.3 × 106 Pa)
Group 2
 Untreated57.3 ± 13.2
( = 1.2 × 106 Pa)
104.7 ± 31.0
( = 1.9 × 106 Pa)
181.0 ± 59.1
( = 3.2 × 106 Pa)
287.7 ± 88.9
( = 5.2 × 106 Pa)
 Treated56.3 ± 6.6
( = 1.1 × 106 Pa)
96.7 ± 12.7
( = 1.7 × 106 Pa)
164.0 ± 27.4
( = 2.8 × 106 Pa)
254.3 ± 37.8
( = 4.5 × 106 Pa)
Group 3
 Untreated52.7 ± 9.6
( = 1.1 × 106 Pa)
94.7 ± 16.5
( = 1.8 × 106 Pa)
160 ± 25.2
( = 3 × 106 Pa)
260.7 ± 40.5
( = 4.9 × 106 Pa)
 Treated88.3 ± 26.3
( = 2 × 106 Pa)
184.3 ± 75.8
( = 3.6 × 106 Pa)
351.7 ± 171
( = 6.3 × 106 Pa)
603.3 ± 316.7
( = 11.0 × 106 Pa)
Group 4
 Untreated63.7 ± 14.0
( = 1.1 × 106 Pa)
112.7 ± 22.4
( = 1.8 × 106 Pa)
187.3 ± 31.6
( = 2.8 × 106 Pa)
292.7 ± 45.5
( = 4.4 × 106 Pa)
 Treated51.7 ± 15.3
( = 0.9 × 106 Pa)
87.0 ± 26.9
( = 1.5 × 106 Pa)
134.0 ± 43.3
( = 2.3 × 106 Pa)
201.3 ± 60.2
( = 3.6 × 106 Pa)

Legenda. : calculated Young’s modulus.