Hypofractionated High-Dose Irradiation with Positron Emission Tomography Data for the Treatment of Glioblastoma Multiforme
Figure 1
An example of the targets planned for a Hypo-IMRT procedure. (a) 11C-Methionine positron emission tomography (MET-PET). (b) Contrast-enhanced T1-weighted magnetic resonance imaging (MRI). Gross tumor volume (GTV) was the area of enhanced lesion on MRI, including MET-PET avid region. Clinical target volume (CTV) was the area with 5 mm margin surrounding the GTV. Both MET-PET moderate region (red line) and the area with 15 mm margin surrounding the CTV (green line) were included in planning target volume. The final determination of target delineation was obtained by consensus among three observers.
