Genotype-Related Effect of Crowding Stress on Blood Pressure and Vascular Function in Young Female Rats

Figure 4

Effect of crowding stress on overall acetylcholine-induced relaxation and its NO-dependent (black bars) and NO-independent (white bars) components in the femoral arteries of Wistar-Kyoto (WKY), borderline hypertensive (BHR), and spontaneously hypertensive (SHR) rats. AUC—area under the curve; a.u.—arbitrary units; NO—nitric oxide; ^x𝑃<0.05 versus WKY respective group (control/stress); ⁺𝑃<0.05 versus BHR respective group (control/stress); ^∗𝑃<0.05 versus control group of the same genotype. Marks above the columns denote differences in overall relaxation and marks in the white (black) part denote differences in NO-independent (NO-dependent) relaxation, respectively. Values represent mean ± SEM of 7–12 rats.