Expression of Stem Cell and Epithelial-Mesenchymal Transition Markers in Circulating Tumor Cells of Breast Cancer Patients

Table 1

CTC detection and characterization markers.

Marker	Reference	CTC detection or enrichment marker	Epithelial marker	Mesenchymal marker	Stem cell marker
Akt2	[17, 19, 20]			x
ALDH1	[17–20, 59, 64, 77, 78]				x
Bmi1	[19]				x
CD133	[18]				x
CD24	[18, 59, 77]				x
CD44	[18, 19, 59, 62, 77]				x
Cytokeratins 8, 18, 19	[24, 61]	x	x
E-cadherin (Cadherin 1)	[69]		x
EGFR	[69]	x	x
EpCAM (GA733-2)	[24, 58, 60, 61, 65, 69]	x	x
Fibronectin 1	[69, 78]			x
FoxC2	[54, 74]			x
HER2	[60, 65, 69]	x	x
MUC1	[60, 65]	x	x
N-cadherin (Cadherin 2)	[69, 75]			x
pan-Cytokeratin	[59, 69]		x
PI3K	[17, 19, 20]			x
SERPINE1/PAI1	[69]			x
SLUG	[54, 74]			x
SNAIL 1	[18, 54, 74, 77]			x
TG2	[18]			x
TWIST 1	[17–20, 54, 74, 76, 77]			x
Vimentin	[75, 76, 78]			x
ZEB1	[18, 54, 74]			x
ZEB2	[54]			x