Comparison of Host Immune Responses to Homologous and Heterologous Type II Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Challenge in Vaccinated and Unvaccinated Pigs

Figure 4

T lymphocyte subpopulations vary between unvaccinated and vaccinated groups and are independent of PRRSV challenge strain. PBMCs were isolated from pigs at necropsy (DPC 14) and T cell subsets were determined by flow cytometry analysis according to their phenotypes. Shown are the percentages of (a) T-helper cells that were CD3⁺/CD4⁺/CD8⁻, (b) Cytotoxic T lymphocytes that were CD⁺CD4⁻CD8⁺, (c) Th/memory cells that were CD3⁺CD4⁺CD8⁺, and (d) 𝛾𝛿 T cells that were CD8⁺TcR1N4⁺. Data were shown as mean ± SEM for 5 pigs per group. *𝑃<0.05.

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