Systemic Approach to Identify Serum microRNAs as Potential Biomarkers for Acute Myocardial Infarction

Table 1

Characteristics of the patients.

	Exploration cohort			Validation cohort
	Ctrl (𝑛=8)	AMI (𝑛=8)	𝑃 value	Ctrl (𝑛=31)	AMI (𝑛=31)	𝑃 value
Age (years)	44.6±10.3	53.3±9.2	0.0980	53.7±14.8	59.0±11.5	0.1235
Male/female (𝑛/𝑛)	6/2	8/0		29/2	29/2
Hypertension (%)	16	20	0.2873	17	19	0.323
Diabetes mellitus	12	14	0.765	11	14	0.635
Hypercholesterolemia	12	14	0.864	14	16	0.123
Smoking	14	14	0.125	14	15	0.110
Troponin I (<0.2 ng/mL)	NA	25.9±65.3		NA	11.7±28.2
Triglyceride (mg/dL)	138.9±73.7	144.0±52.9	0.8750	161.1±94.1	154.0±86.7	0.7685
Cholesterol (mg/dL)	187.0±26.1	164.6±30.9	0.1400	197.9±41.2	160.9±37.8	0.0008
White blood cells (×10^3/uL)	6.35±1.76	11.19±2.19	<0.0001	6.48±1.84	11.15±3.99	<0.0001
Creatinine (md/dL)	0.91±0.22	0.95±0.13	0.6560	0.96±0.22	1.28±1.20	0.1505

Ctrl: control; AMI: acute myocardial infarction; NA: not available; Troponin I was the highest value.