Pathway Gene Gene assignment Transcript cluster ID GenBank number Fold change Histone-related functions HIST2H3D Histone cluster 2, H3d 7919589 NM_001123375 2.48 HIST1H2AI Histone cluster 1, H2ai 8117580 NM_003509 2.69 HIST1H2BH Histone cluster 1, H2bh 8117426 NM_003524 2.31 HIST1H2AK Histone cluster 1, H2ak 8124524 NM_003510 3.66 HIST1H2BK Histone cluster 1, H2bk 8068898 NM_080593 1.98 HIST1H2AI Histone cluster 1, H2ai 8117583 NM_003509 2.31 HIST1H4I Histone cluster 1, H4i 8117537 NM_003495 1.84 HIST1H2BM Histone cluster 1, H2bm 8117594 NM_003521 2.13 HIST2H2AA3 Histone cluster 2, H2aa3 7905079 NM_003516 1.94 HIST2H3A Histone cluster 2, H3a 7905085 NM_001005464 2.60 HIST1H2AH Histone cluster 1, H2ah 8117543 NM_080596 2.83 HIST2H2BE Histone cluster 2, H2be 7919637 NM_003528 2.06 HIST1H3A Histone cluster 1, H3a 8117330 NM_003529 2.00 HIST1H3F Histone cluster 1, H3f 8124437 NM_021018 3.81 HIST1H2BB Histone cluster 1, H2bb 8124394 NM_021062 2.14 HIST1H2BI Histone cluster 1, H2bi 8117429 NM_003525 1.95 HIST1H3G Histone cluster 1, H3g 8124440 NM_003534 2.95 Complement pathway C1S Complement component 1, s subcomponent 7953603 NM_201442
C1R Complement component 1, r subcomponent 7960744 NM_001733
C3 Complement component 3 8033257 NM_000064
MAPK signaling pathway DUSP1 Dual specificity phosphatase 1 8115831 NM_004417 2.96 FOS FBJ murine osteosarcoma viral oncogene homolog 7975779 NM_005252 6.42 MYC V-myc myelocytomatosis viral oncogene homolog 8148317 NM_002467 1.96 JUN Jun protooncogene 7916609 NM_002228 2.02 DUSP6 Dual specificity phosphatase 6 7965335 NM_001946 2.81 SRF Serum response factor (c-fos serum response element-binding transcription factor) 8119712 NM_003131 1.83
Proteasomal pathway SUMO1 SMT3 suppressor of mif two 3 homolog 1 8058335 NM_003352
SNCA Synuclein, alpha (non-A4 component of amyloid precursor) 8101762 NM_000345
PSMD3 Proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 8006984 NM_002809 1.74 PSMB10 Proteasome (prosome, macropain) subunit, beta type, 10 8002133 NM_002801 1.82 PSMA7 Proteasome (prosome, macropain) subunit, alpha type, 7 8067382 NM_002792 1.81
DNA replication MCM5 Minichromosome maintenance complex component 5 8072687 NM_006739 2.05 MCM4 Minichromosome maintenance complex component 4 8146357 NM_005914 2.11 MCM2 Minichromosome maintenance complex component 2 8082350 NM_004526 1.94 Cell cycle CDC25A Homo sapiens cell division cycle 25 homolog A 8086880 NM_001789 2.12 CDC45 Cell division cycle 45 homolog 8071212 NM_001178010 2.00 MYC Homo sapiens v-myc myelocytomatosis viral oncogene homolog 8148317 NM_002467 1.96 ORC1 Origin recognition complex, subunit 1 7916167 NM_004153 1.73
