Singleton Pregnancy Outcomes after In Vitro Fertilization with Fresh or Frozen-Thawed Embryo Transfer and Incidence of Placenta Praevia

Table 4

IVF-ET cycle characteristics resulting in pregnancies with and without placenta praevia.

	Pregnancies with placenta praevia; 𝑁=32	Pregnancies without placenta praevia; 𝑁=1095	𝑃
Day of ET
2	0	14 (1.3%)	0.775
3	0	9 (0.8%)
4	0	1 (<0.1%)
5	32 (100%)	1037 (94.7%)
6	0	34 (3.1%)
Number of morulae and blastocysts on day 5
2 or 3	18 (56%)	610 (56%)	0.410
4 or 5	10 (31%)	258 (23%)
6 or more	3 (3%)	222 (21%)
ET number (1 or 2) and embryo quality (poor/good)**		*
1—poor embryo	0	13 (1%)	0.491
2—poor/poor embryo	3 (9%)	76 (7%)
1—good embryo	6 (19%)	153 (14%)
2—good/poor embryo	2 (6%)	197 (18%)
2—good/good embryo	21 (66%)	461 (42%)
Stimulation protocol		*
Long protocol	18 (56%)	685 (63%)	0.403
Short protocol	14 (44%)	359 (33%)

∗24 data on stimulation in a group of pregnancies without placenta praevia missing and 18 data on embryo quality in group without placenta praevia missing.
**Good quality: good blastocysts quality according to Gardner criteria [24] on day 5 or 6, cleavage stage embryo with little (<10%) or no fragmentation on day 2 or 3, and equal (round) blastomeres on day 2 or 3. Poor quality: embryos not reaching the criteria for good quality.