Antidiabetic Activity of Pterospermum acerifolium Flowers and Glucose Uptake Potential of Bioactive Fraction in L6 Muscle Cell Lines with Its HPLC Fingerprint

Table 1

Effect of ethyl acetate fraction and subfractions of flowers of Pterospermum acerifolium (L.) Willd on changes in blood glucose level during OGTT.

Treatment	Blood glucose level (mg/dL)
	0th min	30th min	60th min	120th min
Normal control	75.2 ± 0.477	144.2 ± 0.477	139.2 ± 1.046	121.2 ± 1.600
Diabetic control	353 ± 11.8^aaaa	442.8 ± 16.22^aaaa	439.7 ± 18.97^aaaa	398.2 ± 12.96^aaaa
PAFEF1	234.6 ± 5.02	301 ± 5.373	278.8 ± 6.582	266.5 ± 7.602
PAFEF2	233 ± 16.8	292.2 ± 16.11	262.7 ± 15.95	249 ± 16.48
PAFE1-1	226 ± 7.44	278.8 ± 6.258	260.2 ± 8.845	246.5 ± 7.610
PAFE1-2	235 ± 13.5	285.7 ± 15.82	260.7 ± 15.68	249.7 ± 14.71
PAFE2-1	221 ± 6.11	275 ± 8.418	253.3 ± 7.032	236.5 ± 9.021
PAFE2-2	194 ± 7.77^bb	247.7 ± 6.556^bbb	221.3 ± 5.760^bb	200 ± 7.554^bb
PAFE3-1	269 ± 11.3^aa	318.5 ± 15.64^aa	313.3 ± 12.30^aaa	309.3 ± 14.18^aaa
PAFE3-2	264 ± 9.77^aa	314.8 ± 9.365^a	306 ± 10.17^aa	295.8 ± 9.203^aa
STD drug	176 ± 6.90^bbb	225 ± 4.892^bbbb	193 ± 4.235^bbb	177.3 ± 8.773^bbb

The results are expressed as mean ± standard error of the mean (SEM). Probability values of   < 0.0001, ^aaa < 0.001, ^aa < 0.01, and ^a < 0.05 were compared with normal control. Probability values of  ^bbbb < 0.0001, ^bbb < 0.001, ^bb < 0.01, and ^b < 0.05 were compared with disease control.