Antidiabetic Activity of Pterospermum acerifolium Flowers and Glucose Uptake Potential of Bioactive Fraction in L6 Muscle Cell Lines with Its HPLC Fingerprint

Table 2

Effect of ethyl acetate fraction and subfractions of flowers of Pterospermum acerifolium (L.) Willd on changes in blood glucose level.

Treatment	Blood glucose level (mg/dL)
	Day 0	Day 14	Day 21	Day 28
Normal control	68.83 ± 1.014	75.33 ± 0.494	74.50 ± 0.428	73.83 ± 1.4
Diabetic control	296.5 ± 9.454	351.2 ± 11.84^aaaa	360.7 ± 6.075^aaaa	405.7 ± 6.344^aaaa
PAFEF1	286.2 ± 8.975	238.8 ± 6.983	207.8 ± 7.674	183.7 ± 4.240
PAFEF2	302.3 ± 11.12	234.8 ± 16.8	205.7 ± 13.95	176.5 ± 9.942
PAFE1-1	285.2 ± 6.858	226.8 ± 7.726	200.2 ± 4.658	178.5 ± 8.655
PAFE1-2	300.7 ± 10.08	236.5 ± 13.25	207.3 ± 11.07	181.8 ± 8.623
PAFE2-1	282.8 ± 12.74	225 ± 8.629	180.5 ± 5.596^b	151.8 ± 6.030^bb
PAFE2-2	285 ± 7.904	193.5 ± 7.775^bb	152 ± 6.698^bbb	120.8 ± 5.375^bbb
PAFE3-1	296.5 ± 10.30	270.7 ± 11.41^aa	256.7 ± 10.74^aaa	248.2 ± 10.99^aaa
PAFE3-2	279.7 ± 11.26	265.3 ± 9.790^aa	239 ± 12.40^aa	229.5 ± 11.49^aaa
STD drug	290.2 ± 7.115	178.5 ± 7.758^bbb	134.5 ± 4.137^bbb	106.5 ± 3.166^bbb

The results are expressed as mean ± standard error of the mean (SEM). Probability values of   < 0.0001, ^aaa < 0.001, ^aa < 0.01, and ^a < 0.05 were compared with normal control. Probability values of  ^bbbb < 0.0001, ^bbb < 0.001, ^bb < 0.01, and ^b < 0.05 were compared with disease control.