Antidiabetic Activity of Pterospermum acerifolium Flowers and Glucose Uptake Potential of Bioactive Fraction in L6 Muscle Cell Lines with Its HPLC Fingerprint
Table 3
Effect of ethyl acetate fraction and subfractions of flowers of Pterospermum acerifolium (L.) Willd on body weight changes and glycosylated Hb.
Treatment
Body weight (gms)
Glycosylated Hb (%)
Initial
Final
Normal control
197.5 ± 2.707
241.1 ± 2.740
2.872 ± 0.277
Diabetic control
198.4 ± 4.845
149.7 ± 6.182
7.932 ± 0.109aaaa
PAFEF1
200.9 ± 3.605
205.2 ± 2.968
5.680 ± 0.060
PAFEF2
197.9 ± 5.206
210.7 ± 6.634
5.412 ± 0.023b
PAFE1-1
199.1 ± 4.202
201.3 ± 4.148
6.417 ± 0.067aa
PAFE1-2
199.9 ± 3.738
206.3 ± 3.983
5.892 ± 0.104
PAFE2-1
193.4 ± 2.815
201.8 ± 3.445
4.708 ± 0.055bb
PAFE2-2
199.9 ± 2.854
219.3 ± 3.157
4.227 ± 0.075bbb
PAFE3-1
203.7 ± 2.749
183.4 ± 3.410
6.770 ± 0.278aa
PAFE3-2
197.3 ± 2.953
184.4 ± 4.275
6.690 ± 0.049aaa
STD drug
203.2 ± 2.793
231.7 ± 3.740
3.337 ± 0.097bbbb
The results are expressed as mean ± standard error of the mean (SEM). Probability values of < 0.0001, aaa < 0.001, aa < 0.01, and a < 0.05 were compared with normal control. Probability values of bbbb < 0.0001, bbb < 0.001, bb < 0.01, and b < 0.05 were compared with disease control.
