Elastase and Cathepsin G from Primed Leukocytes Cleave Vascular Endothelial Cadherin in Hemodialysis Patients
Figure 4
Soluble VE-cadherin fragments (140 and 100 kDa forms) in HD plasma versus NC plasma.Proteins of plasma samples depleted from albumin and immunoglobulins of NC subjects and HD patient were separated on SDS-PAGE followed by western blot analysis (a) Representative gels showing three sizes of VE-cadherin: the whole molecule: 140 kDa and the cleaved forms: 100 and 40 kDa in NC (1,3) and HD plasma (2,4). (b) Relative densities of VE-cadherin from NC subjects and HD patient plasma ( HD versus NC; ).
