Solubility and Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin: <i>In Vitro</i>, <i>Ex Vivo</i>, and <i>In Vivo</i> Studies

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Drug/polymer ratio</td><td align="center"><svg height="11.75" id="M50" style="vertical-align:-0.23827pt" version="1.1" viewbox="0 0 12.975 11.75" width="12.975" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> solubility enhancement</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">1 : 1</td><td align="center">63.4</td></tr><tr><td align="left">1 : 3</td><td align="center">77.6</td></tr><tr><td align="left">1 : 6</td><td align="center">84.3**</td></tr><tr><td align="left">1 : 9</td><td align="center">85.8**</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><svg height="13.95" id="M51" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 73.300003 13.95" width="73.300003" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>; ATR: atorvastatin; NG: Neem Gum.<br/></td></tr></table>

BioMed Research International

tab4

Table 4

Table 4: Solubility and Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin: <i>In Vitro</i>, <i>Ex Vivo</i>, and <i>In Vivo</i> Studies 

BioMed Research International

Solubility and Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin: In Vitro, Ex Vivo, and In Vivo Studies

Table 4