Solubility and Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin: In Vitro, Ex Vivo, and In Vivo Studies

Table 6

Drug content and dissolution efficiency of KM and SE before and after stability.

Formulation	Drug content	DE 30 min	DE 120 min
0 months KM (1 : 6)	100.47±0.12	88.47±2.13	97.84±1.23
After 3 months study KM (1 : 6)	99.84±0.04	86.94±0.42	99±0.014
0 months study SE (1 : 6)	100.81±0.01	100.82±0.13	101±1.23
After 3 months study SE (1 : 6)	100±0.13	100.1±1.42	101±0.014

𝑛=3.
KM: kneading method; SE: solvent evaporation method.