Research Article

An Update of the Interstitial Cell Compartment in the Normal Human Bladder

Figure 3

Double staining of N-cadherin and vimentin. (a) Two suburothelial cells coexpressing N-cadherin (green) and vimentin (red) are closely associated with each other (arrowhead). (b) Note punctate pattern of N-cadherin in contrast to the vimentin+ filaments, which both are expressed within the same cell body. Magnification ×1000. (c) Multiple elongated N-cadherin+/vimentin+ containing cells are closely associated at the border of detrusor smooth muscle bundles. (d) Detrusor fascicles show numerous N-cadherin+/vimentin+ processes (arrows) running between muscle cells. Magnification ×630. (e) Higher magnification shows expression of N-cadherin that is located at the cell membrane of some vimentin+ cells. Magnification ×1000. (f) Two cells localized at the edge of a smooth muscle fascicle. N-cadherin+/vimentin− cell is neighboured by a N-cadherin−/vimentin+ cell. Magnification ×1000.
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