Induction of Apoptosis of 2,4′,6-Trihydroxybenzophenone in HT-29 Colon Carcinoma Cell Line
Figure 3
(a) Mass-spectrum of gas chromatography mass spectrometry (GC-MS) analysis of 2,4′,6-trihydroxy-4-methoxybenzophenone, (b) In vitro, cytotoxic effects of 2,4′,6-trihydroxy-4-methoxybenzophenone on (b) HT-29 colon cancer cells, (c) MRC-5 normal lung cells and (d) WRL-68 normal fibroblast cells. Cells were treated with various concentrations of 2,4,6′-trihydroxy-4-methoxybenzophenone from ethyl acetate fraction of Phaleria macrocarpa (Scheff.) Boerl. fruits for 24 h, 48 h, and 72 h prior to the determination of cytotoxicity by MTT cell proliferation assay. Each value is expressed as mean ± standard deviation of three measurements.
