Toxicity Profile of a Nutraceutical Formulation Derived from Green Mussel Perna viridis

Table 2

Hematology analyses data of male and female rats administered the green mussel formulation after subchronic (90 days) toxicity studies.

Treatments		Lymphocytes (mm^3)	Eosinophils (mm^3)	Neutrophils (mm^3)	HGB (g/dL)	WBC (mm^3)	RBC (10^6/cmm)	Platelet (10^5/cmm)
Male	Control^a	5828.60±159.14	998.20±62.90	3213.20±17.13	15.44±0.05	10040±58.6	7.87±0.07	5.78±0.06
	2.0 g/kg^b	4638.00±154.50	752.60±31.57	2329.40±83.04^∗	14.60±0.64	7720±26.70	7.41±0.29	4.64±0.38
	1.0 g/kg^b	3643.80±187.47^∗	618.60±33.24^∗	2017.60±88.02^∗	14.34±0.73	6280±30.90	7.29±0.58	5.08±0.04
	0.5 g/kg^b	4912.20±114.07	773.60±15.38	2754.20±78.98	14.64±0.70	8440±174.70	7.27±0.08	5.78±0.06
Female	Control^a	5220.40±231.0	888.80±37.78	2730.80±80.31	13.38±0.94	8840±148.9	6.37±0.47	6.06±0.03
	2.0 g/kg^b	3856.40±167.93^∗	645.40±28.94	2298.20±114.25	14.12±0.44	6800±97.7	6.97±0.03	5.78±0.08
	1.0 g/kg^b	4975.20±269.33	770.00±31.75	1974.80±83.87^∗	13.86±0.83	7720±107.5	6.86±0.21	5.30±0.07
	0.5 g/kg^b	2122.80±101.52^∗	321.20±14.67^∗	1096.00±50.93^∗	13.54±0.53	3540±101.7^∗	6.77±0.07	5.64±0.06

∗Data presented as mean ± standard deviation (𝑛=5). Significantly different from control: 𝑃<0.05.
^aControl group received 1 mL distilled water.
^bSample group received three doses of green mussel formulation (2.0, 1.0, and 0.5 g/kg rat).
HGB: hemoglobin; WBC: total white blood cell count; RBC: red blood cell.