Fatty Acids in Energy Metabolism of the Central Nervous System

Figure 10

A schematic presentation of operation of the tricarboxylic acid cycle in brain mitochondria oxidizing glutamate and pyruvate. The figure was adapted from [95]. Abbreviations: AST: aspartate aminotransferase, ALT: alanine aminotransferase, and SDH: succinate dehydrogenase. The symbol of the closed lock means the step catalyzed by SDH is inhibited. The dashed arrows indicate inhibitory influences of malate and oxaloacetate on SDH.