Computational Study to Determine When to Initiate and Alternate Therapy in HIV Infection
Table 3
Monte Carlo simulation outcome for SVF and SWATCH strategies.
(a) SVF
(years)
(years)
0.5
14.01 ± 4.34
298
1
13.93 ± 4.39
292
1.5
13.82 ± 4.43
284
2
13.61 ± 4.38
277
3*
13.06 ± 4.08
259
4*
12.83 ± 4.55
253
(b) SWATCH
(years)
(years)
0.5
15.54 ± 4.79
466
1
15.45 ± 4.81
454
1.5
15.13 ± 4.79
442
2*
14.69 ± 4.68
427
3*
13.67 ± 4.38
386
4*
12.59 ± 3.84
336
is the average year when immunological failure occurs for the 1000 random samples and the respective standard deviation . is the number of cases that do not experience immunological failure after 30 years postinfection. *Star represents a statistically significant difference with respect to the group of years (). There is a significant difference between SWATCH and SVF for all the groups when .