Peripheral Injection of SB203580 Inhibits the Inflammatory-Dependent Synthesis of Proinflammatory Cytokines in the Hypothalamus
Figure 1
Effect of lipopolysaccharide (LPS) (400 ng/kg; i.v./7 days) and SB203580 (500 μg/kg) injections on IL-1β (a), IL-6 (b), and TNFα (c) expression in the hypothalamus on day 7 of the experiment. a, b, c— (indicate values that differ significantly from the control, SB203580 control, and LPS treated groups, resp., according to the Mann-Whitney test). Data are presented as a mean value ± S.E.M.
