Preliminary In Vitro and In Vivo Evaluation of Antidiabetic Activity of Ducrosia anethifolia Boiss. and Its Linear Furanocoumarins

Table 6

Effect of Ducrosia anethifolia total extract on total urea and creatinine levels in STZ-induced diabetes in rats.

Groups	Parameters
	Normal control	D. anethifolia treated normal	STZ treated	STZ + D. anethifolia treated	STZ + glibenclamide
Total urea	36.00±6.10^a	34.20±3.80^a	89.00±2.80^b	46.45±3.07^c	33.23±6.90^a
Creatinine	0.84±0.04^a	0.80±0.05^a	3.90±0.20^b	1.09±0.12^c	0.80±0.04^a

Data are means ± SD of ten rats in each group. Total urea and creatinine are expressed in mg/dL.
Statistical analysis is carried out using CoStat Computer Program coupled with post hoc (least significance difference LSD). The different groups were compared with each other at the same time and the unshared letter is significantly different at 𝑃≤0.05.