Merit of Ginseng in the Treatment of Heart Failure in Type 1-Like Diabetic Rats

Table 1

Characteristics of normal rats, diabetic rats, and ginseng-treated diabetic rats.

Parameters	Normal rats	Diabetic rats	Ginseng-treated diabetic rats
Food intake (g/day)	23.8±3.6	42.5±8.3^∗∗	43.6±4.7^∗∗
Water intake (g/day)	41.5±6.9	176.3±11.9^∗∗	178.2±11.3^∗∗
Plasma glucose (mmol/L)	5.8±0.7	30.4±3.8^∗∗∗	31.2±2.8^∗∗∗
Body weight (g)	386.8±13.5	247.6±11.2^∗∗	253.4±14.6^∗∗
Systolic blood pressure (mmHg)	117.3±3.6	84.5±8.2^∗∗	109.8±4.7^##
Diastolic blood pressure (mmHg)	81.7±5.4	51.9±7.2^∗∗	78.7±7.6^##
Heart rate (beats/min)	374.7±23.2	303.4±18.6^∗	297.3±14.5^#
Cardiac output (mL/min)	24.7±0.5	12.4±0.8^∗	19.2±0.7^##

Values were obtained from normal rats, vehicle-treated diabetic rats and ginseng-treated diabetic rats. All values were presented as mean ± SEM (𝑛=6 per group). The ginseng-treated group received the ginseng (150 mg/kg/day, orally for 7 days). *𝑃<0.05, **𝑃<0.01, and ***𝑃<0.001 as compared with normal rats. ^#𝑃<0.05 and ^##𝑃<0.01 as compared with vehicle-treated diabetic rats.