Clinical Study

Thai Massage, and Thai Herbal Compress versus Oral Ibuprofen in Symptomatic Treatment of Osteoarthritis of the Knee: A Randomized Controlled Trial

Table 3

Mean VAS assessing pain (mm) in intent-to-treat patients ().

VariableTreatment groupWeek 0 Week 1Week 2Week 3

VAS assessing pain (mm)
 Walking painTM58.05 ± 13.4842.45 ± 15.02***26.60 ± 12.19***17.70 ± 15.01***
THC61.40 ± 17.9439.00 ± 18.91***26.70 ± 16.66***16.35 ± 17.54***
Ibuprofen53.35 ± 13.7036.40 ± 16.48**28.75 ± 16.47***19.85 ± 17.96***
 Standing painTM55.10 ± 13.2938.25 ± 20.88***26.90 ± 19.15***20.05 ± 21.69***
THC54.85 ± 19.8040.75 ± 19.19**26.35 ± 17.81***16.70 ± 15.69***
Ibuprofen52.50 ± 18.8435.45 ± 16.89**26.85 ± 18.63***19.80 ± 17.84***
 Pain during climbing up and down stairsTM55.80 ± 20.7545.50 ± 22.19**31.75 ± 20.26***23.65 ± 16.91***
THC62.80 ± 21.2242.50 ± 18.03***29.00 ± 15.40***14.20 ± 11.52***
Ibuprofen58.20 ± 22.3743.95 ± 22.36**32.90 ± 22.99***25.25 ± 21.76***
 Night painTM54.60 ± 20.3532.75 ± 19.25***19.10 ± 21.40***14.60 ± 20.57***
THC40.00 ± 26.2827.40 ± 23.25**16.00 ± 19.16***5.75 ± 9.16***
Ibuprofen50.20 ± 19.8129.80 ± 16.58***18.55 ± 20.05***14.20 ± 18.13***
 Resting painTM35.65 ± 18.8326.80 ± 16.5915.20 ± 15.26**11.95 ± 14.46**
THC41.20 ± 21.8822.45 ± 19.87**11.10 ± 14.28***8.55 ± 11.07***
Ibuprofen39.50 ± 18.8124.60 ± 17.39***20.05 ± 16.12**9.80 ± 13.92***
 Total painaTM259.20 ± 56.20185.75 ± 67.31***119.55 ± 71.98***87.95 ± 75.81***
THC260.25 ± 68.86172.10 ± 73.42***109.15 ± 61.56***61.55 ± 49.42***
Ibuprofen253.75 ± 63.45170.20 ± 62.85***107.40 ± 82.15***69.20 ± 71.02***
 Pain during the most painful knee movementTM74.60 ± 14.3459.05 ± 17.89**45.50 ± 24.66***31.15 ± 22.30***
THC76.70 ± 14.9448.35 ± 25.70***28.60 ± 20.24***22.60 ± 19.91***
Ibuprofen76.95 ± 14.0749.90 ± 23.72***36.20 ± 24.71***29.55 ± 25.60***

Data represent mean ± SD. aSummation of VAS that assessed walking pain, standing pain, pain during climbing up and down stairs, night pain, and resting pain. *P < 0.05, **P < 0.01, ***P < 0.001 versus baseline.