Thai Massage, and Thai Herbal Compress versus Oral Ibuprofen in Symptomatic Treatment of Osteoarthritis of the Knee: A Randomized Controlled Trial

Table 5

Mean changes from baseline in VAS assessing pain in intent-to-treat patients ().

Variable	Treatment group	Week 0-1	Week 0–2	Week 0–3
VAS assessing pain (mm)
Walking pain	TM	−15.60 ± 15.25	−31.45 ± 13.33	−40.35 ± 15.55
	THC	−22.40 ± 14.09	−34.70 ± 18.70	−45.05 ± 18.76
	Ibuprofen	−16.95 ± 18.35	−24.60 ± 22.83	−33.50 ± 23.80
Standing pain	TM	−16.85 ± 17.28	−28.20 ± 14.06	−35.05 ± 16.32
	THC	−14.10 ± 15.21	−28.50 ± 21.54	−38.15 ± 20.25
	Ibuprofen	−17.05 ± 20.01	−25.65 ± 23.39	−32.70 ± 26.35
Pain during climbing up and down stairs	TM	−10.30 ± 11.07	−24.05 ± 17.40	−32.15 ± 19.01
	THC	−20.30 ± 15.84^†	−33.80 ± 21.20	−48.60 ± 19.45^*,†
	Ibuprofen	−14.25 ± 17.14	−25.30 ± 23.59	−32.95 ± 26.07
Night pain	TM	−21.85 ± 14.80	−35.50 ± 24.59	−40.00 ± 25.16
	THC	−12.60 ± 16.48	−24.00 ± 21.68	−34.25 ± 25.32
	Ibuprofen	−20.40 ± 19.73	−31.65 ± 23.72	−36.00 ± 23.40
Resting pain	TM	−8.85 ± 21.59	−20.45 ± 24.80	−23.70 ± 27.53
	THC	−18.75 ± 26.76	−30.10 ± 24.60	−32.65 ± 24.10
	Ibuprofen	−14.90 ± 12.86	−19.45 ± 21.22	−29.70 ± 24.02
Total pain^a	TM	−73.45 ± 38.70	−139.65 ± 63.68	−171.25 ± 71.94
	THC	−88.15 ± 54.65	−151.10 ± 70.92	−198.70 ± 71.19
	Ibuprofen	−83.55 ± 64.06	−146.35 ± 94.02	−184.55 ± 92.36
Pain during the most painful knee movement	TM	−15.55 ± 19.69	−29.10 ± 25.14	−43.45 ± 23.00
	THC	−28.35 ± 19.00	−48.10 ± 18.52^†	−54.10 ± 17.94
	Ibuprofen	−27.05 ± 21.85	−40.75 ± 23.97	−47.40 ± 26.85

Data represent mean ± SD. ^aSummation of VAS that assessed walking pain, standing pain, pain during climbing up and down stairs, night pain, and resting pain. *Statistical significance versus ibuprofen (P = 0.027). ^†Statistical significance versus TM (P = 0.038 and P = 0.020; pain during climbing up and down stairs at week 0-1 and 0–3, respectively, P = 0.011; pain during the most painful knee movement at week 0–2).