Development and Maturation of the Immune System in Preterm Neonates: Results from a Whole Genome Expression Study
Table 2
Summary of the number of differentially expressed genes between the studied groups.
Comparison
adjusted for multiple comparison
; fold change >1.5
5th DOL
Genes presented a positive monotone trend (expression in extremely preterm is lower than that in very preterm; expression in very preterm is lower than that in moderately preterm)
56
Genes presented a negative monotone trend
82
28th DOL
Genes presented a positive monotone trend
253
Genes presented a negative monotone trend
55
5th DOL versus 28th DOL (paired -test)
Genes whose expressions were significantly higher on the 28th DOL compared to those on the 5th DOL
1522
150
Genes whose expressions were significantly lower on the 28th DOL compared to those on the 5th DOL
2909
337
Extremely preterm infants measurement on the 28th DOL versus very preterm infants measurements on the 5th DOL
Genes whose expressions were significantly higher in the group of extremely preterm infants compared to those in the group of very preterm infants
176
29
Genes whose expressions were significantly lower in the group of extremely preterm infants compared to those in the group of very preterm infants