Noncoding RNAs: Emerging Players in Muscular Dystrophies

Table 1

Deregulated noncoding RNAs in skeletal muscle tissue.

Muscular dystrophy	Deregulated noncoding RNAs	References
DMD/mdx mice	UP: miR-21, miR-206, miR-199a-5p, miR-222, miR-31, miR-34c, miR-335, miR-379, miR-449, and miR-494	[28–36]
	DOWN: miR-22, miR-30a-3p, miR-486, miR-1, miR-29c, miR-135a, and linc-MD1
DM1	UP: miR-206, miR-1, and miR-335	[37–40]
	DOWN: miR-29b, miR-29c, miR-33, miR-7, and miR-10
DM2	UP: miR-221-3p, miR-34c-5p, miR-208a, miR-381, miR-34b-3p, miR-34a-5p, and miR-146b-5p	[41]
	DOWN: miR-193b-3p, miR-125b-5p, miR-378a-3p, and miR-193a-3p
FSHD	UP: miR-1, miR-206, miR-133a, miR-133b, miR-7, miR-15a, miR-21, miR-22, miR-30e, miR-32, miR-107, miR-139, miR-152, miR-223, miR-302b, miR-331, miR-362, miR-365, miR-382, miR-496, miR-532, miR-654, and miR-660	[30, 42]
	DOWN: miR-15b, miR-20b, miR-21, miR-25, miR-100, miR-155, miR-345, and miR-594

Only miRNAs validated either by more than one study or by one study using two independent techniques are indicated.