Noncoding RNAs: Emerging Players in Muscular Dystrophies

Table 2

Deregulated noncoding RNAs in serum.

Muscular dystrophy	Deregulated noncoding RNAs	References
DMD/mdx mice	UP: miR-1, miR-133a, miR-133b, miR-206, miR-378, miR-193b, miR-30d, miR-149, miR-30a, miR-434-3p, miR-146b, and miR-30e	[36, 43, 44]
	DOWN: miR-122, miR-429, miR-200a, miR-672, miR-31, miR-451, miR-143, miR-195, miR-148a, let-7g, miR-125b-5p, miR-200b, miR-145, miR-142-3p, let-7b, miR-26b, miR-152, let-7i, and miR-301b
LGMD2D; (Sgca-null mice)	UP: miR-206, miR-133a, miR-133b, miR-1, miR-378, miR-193b, miR-149, miR-30a, miR-30d, miR-709, and miR-30e	[44]
	DOWN: miR-122, miR-672, miR-125a-5p, miR-200a, miR-199a-3p, miR-195, miR-429, miR-151-3p, miR-31, miR-26a, miR-125b-5p, miR-142-3p, miR-152, miR-301b, miR-93-3p, and miR-200b
LGMD2C; (Sgcg-null mice)	UP: miR-133a, miR-133b, miR-206, miR-1, miR-378, miR-30d, miR-193b, miR-22, miR-149, miR-30a, and miR-106a	[44]
	DOWN: miR-125a-5p, miR-31, miR-26b, miR-142-3p, miR-429, miR-26a, miR-200a, miR-122, miR-672, miR-let-7g, miR-125b-5p, miR-let-7b, miR-let-7i, miR-215, and miR-301b
EDMD; (KI-Lmna mice)	UP: miR-146b and miR-200a	[44]
	DOWN: miR-130a, miR-133a, miR-133b, miR-1, miR151-3p, and miR-339-3p

Only miRNAs validated either by more than one study or by one study using two independent techniques are indicated.