An Association Study between Genetic Polymorphism in the Interleukin-6 Receptor Gene and Coronary Heart Disease

Table 3

Post hoc analysis of rs7529229 with the risk of CHD in different age subgroups.

Age group	Genotype (TT/TC/CC)	𝜒^2	𝑃 (df = 2)	HWE	Allele (𝑇/𝐶)	𝜒^2	𝑃 (df = 1)	OR (95% CI)
≤55 CHD cases (𝑛=70)	19/37/14			0.80	75/65
≤55 controls (𝑛=71)	25/36/10	1.49	0.47	0.80	86/56	1.40	0.23	0.75 (0.46–1.20)
55–65 CHD cases (𝑛=95)	23/50/22			0.68	96/94
55–65 controls (𝑛=82)	25/39/18	0.89	0.64	0.82	89/75	0.49	0.48	0.86 (0.56–1.30)
≥65 CHD cases (𝑛=98)	35/46/17			0.83	116/80
≥65 controls (𝑛=43)	13/23/7	0.54	0.76	0.75	49/37	0.12	0.72	1.09 (0.65–1.82)