Enhanced Analgesic Properties and Reduced Ulcerogenic Effect of a Mononuclear Copper(II) Complex with Fenoprofen in Comparison to the Parent Drug: Promising Insights in the Treatment of Chronic Inflammatory Diseases
Scheme 2
Proposed mechanism for the incremented analgesic activity of [Cu(fen)2(im)2] in comparison to the uncomplexed commercial parent drug (COX-2: cyclooxygenase-2; PG: prostaglandins; SOD: superoxide dismutase).
