Antioxidant and Prophylactic Effects of Delonix elata L., Stem Bark Extracts, and Flavonoid Isolated Quercetin against Carbon Tetrachloride-Induced Hepatotoxicity in Rats
Table 3
In vitro antioxidant activity of D. elata stem bark extracts.
Serial number
Activity
Concentration of extracts in g
% of inhibition
DSP
DSC
DSE
1
DPPH radical scavenging activity
50
2.49 ± 0.11
15.73 ± 0.37
34.36 ± 0.01
100
5.22 ± 0.22
27.49 ± 0.05
60.91 ± 0.33
150
8.57 ± 0.56
47.29 ± 0.31
85.71 ± 0.05
2
Superoxide radical scavenging activity
100
1.27 ± 0.17
20.65 ± 0.35
37.22 ± 0.21
200
4.50 ± 0.28
44.36 ± 0.21
58.60 ± 0.01
300
6.44 ± 0.09
64.43 ± 0.43
83.56 ± 0.34
3
Hydroxyl radical scavenging assay
100
2.53 ± 0.07
10.83 ± 0.28
22.2 ± 0.01
250
5.58 ± 0.09
23.48 ± 0.41
39.13 ± 0.32
500
10.37 ± 0.13
47.52 ± 0.05
77.34 ± 0.18
4
Nitric oxide radical scavenging activity
100
2.53 ± 0.07
10.83 ± 0.28
22.20 ± 0.01
250
5.58 ± 0.09
23.48 ± 0.41
39.13 ± 0.32
500
10.37 ± 0.13
47.52 ± 0.05
77.34 ± 0.18
5
Metal chelating
1000
0.47 ± 0.03
7.51 ± 0.39
27.29 ± 0.29
2000
2.80 ± 0.05
15.43 ± 0.34
49.36 ± 0.16
3000
4.46 ± 0.03
22.12 ± 0.09
65.44 ± 0.16
6
Lipid peroxidation inhibition
500
1.62 ± 0.26
12.33 ± 0.09
19.6 ± 0.38
1000
3.42 ± 0.03
23.62 ± 0.18
35.30 ± 0.59
1500
4.58 ± 0.14
31.15 ± 0.26
51.58 ± 0.12
The results shown are averages of three independent experiments; values are mean ± SEM.
