Antioxidant and Prophylactic Effects of Delonix elata L., Stem Bark Extracts, and Flavonoid Isolated Quercetin against Carbon Tetrachloride-Induced Hepatotoxicity in Rats
Table 4
IC50 values of stem bark extracts of D. elata for in vitro antioxidant activity.
Serial number
Activity
DSP (g)
DSC (g)
DSE (g)
Standard (g)
1
DPPH radical scavenging
922.1 ± 6.05
165.72 ± 0.2
82.88 ± 0.18
85.26 ± 0.41 (BHT)
2
Superoxide radical scavenging
2459.02 ± 6.04
231.78 ± 1.78
167.24 ± 0.12
101.13 ± 1.0 (Ascorbic acid)
3
Hydroxyl radical scavenging
2852.72 ± 32.55
681.75 ± 6.62
423.43 ± 0.38
125.66 ± 1.2 (BHT)
4
Nitric oxide radical scavenging
2300.14 ± 2.86
519.4 ± 1.18
306.48 ± 1.10
98.34 ± 0.74 (Curcumin)
5
Metal chelating
38861.15 ± 21.35
6659.84 ± 13.87
2111.23 ± 4.42
31.52 ± 0.2 (EDTA)
6
Lipid peroxidation inhibition
10409.9 ± 29.66
1490.42 ± 3.66
939.15 ± 9.61
—
The results shown are averages of three independent experiments; values are mean ± SEM. BHT-vutylated hydroxytoluene; EDTA-ethylenediaminetetra acetic acid.