Role of Dried Fruits of Carissa carandas as Anti-Inflammatory Agents and the Analysis of Phytochemical Constituents by GC-MS

Table 3

Anti-inflammatory activity of methanol extract of dried fruit of Carissa carandas.

Group	Sample	Amount of sample	Increase in paw volume (min)				% decrease in paw volume
			30	60	90	120
I	Control	1 mL/kg	0.198 ± 0.01	0.35 ± 0.027	0.64 ± 0.021	0.77 ± 0.005	—
II	Standard	50 mg/kg	0.13 ± 0.021**	0.17 ± 0.016**	0.35 ± 0.021**	0.27 ± 0.016**	80.63
III	Methanol extract	100 mg/kg	0.21 ± 0.005**	0.29 ± 0.005**	0.48 ± 0.005**	0.57 ± 0.005**	33.7
IV	Methanol extract	200 mg/kg	0.19 ± 0.01**	0.22 ± 0.01**	0.4 ± 0.01**	0.45 ± 0.01**	60.95
V	Methanol extract	400 mg/kg	0.17 ± 0.01**	0.2 ± 0.01**	0.34 ± 0.05**	0.37 ± 0.01**	76.12

∗∗The mean difference is significant at the 0.05 level, when compared to the control group.